Amantadine and Rimantadine Analogues—Single-Crystal Analysis and Anti-Coronaviral Activity

Amantadine and Rimantadine Analogues—Single-Crystal Analysis and Anti-Coronaviral Activity

In this study, we utilized the human coronavirus 229E (HCoV-229E) for evaluating the in vitro efficacy of some analogues of the ion-channel inhibitors and Amantadine and Rimantadine. The application of these investigated compounds did not result in any detectable cytotoxic effects. Furthermore, we o...

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Bibliographic Details
Main Authors: Kalina Shishkova, Antoniya Stoymirska, Radoslav Chayrov, Stoyan Shishkov, Hristina Sbirkova-Dimitrova, Rusi Rusew, Boris Shivachev, Ivanka Stankova
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Crystals
Subjects:
Amantadine
Rimantadine
X-ray analysis
antiviral activity
coronavirus
Online Access:https://www.mdpi.com/2073-4352/13/9/1374

Internet

https://www.mdpi.com/2073-4352/13/9/1374

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