Rapid tests reduce the burden of tuberculosis in Azerbaijan prisons: special emphasis on rifampicin-resistance

ABSTRACT Aims To evaluate the impact of addition of rapid tests for tuberculosis (TB) to mass screening and passive case finding on the burden of TB in high-incidence prisons of Azerbaijan. Materials and methods All new and relapse TB cases notified in 01.01.2009-31.12.2015 were retrospectively in...

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Main Authors: E Gurbanova, R Mehdiyev, K Blondal, A Altraja
Format: Article
Language:English
Published: Sociedad Española de Sanidad Penitenciaria
Series:Revista Española de Sanidad Penitenciaria
Subjects:
Online Access:http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1575-06202018000300111&lng=en&tlng=en
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author E Gurbanova
R Mehdiyev
K Blondal
A Altraja
author_facet E Gurbanova
R Mehdiyev
K Blondal
A Altraja
author_sort E Gurbanova
collection DOAJ
description ABSTRACT Aims To evaluate the impact of addition of rapid tests for tuberculosis (TB) to mass screening and passive case finding on the burden of TB in high-incidence prisons of Azerbaijan. Materials and methods All new and relapse TB cases notified in 01.01.2009-31.12.2015 were retrospectively included. Results 2,315 TB patients were identified in 19 prisons. Implementation of the rapid tests to the case finding algorithms lead to 3-, 10- and 5-fold decrease in the annual rates of the notified, smear-positive and RIF-resistant TB cases, respectively. After introduction of rapid tests into the screening algorithms, there were significant linear trends towards decrease in the notified (p=0.009), smear-positive (p=0.011) and RIF-resistant TB cases (p=0.02) with the annual rates of decrease (95% confidence interval (CI)) being -435 (-614; -255), -356 (-517; -195), and -99 (-160; -38), respectively. Utilization of rapid tests also significantly increased treatment success with first-line drugs among all cases, cases detected by mass screening and those, detected by passive case finding [adjusted odds ratio (aOR)=2.38, 95% CI:1.86-3.05, aOR=4.56, 95% CI:2.64-7.89 and aOR=2.60, 95% CI:1.81-3.75, respectively]. Conclusions Introduction of rapid tests into the screening lead to decline in the burden of TB and RIF-resistance, and improved outcomes of treatment with first-line drugs in prisons.
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spelling doaj.art-51700686018a46bfba7b0af6c4d5e2bf2022-12-21T19:56:17ZengSociedad Española de Sanidad PenitenciariaRevista Española de Sanidad Penitenciaria2013-6463203111120S1575-06202018000300111Rapid tests reduce the burden of tuberculosis in Azerbaijan prisons: special emphasis on rifampicin-resistanceE GurbanovaR MehdiyevK BlondalA AltrajaABSTRACT Aims To evaluate the impact of addition of rapid tests for tuberculosis (TB) to mass screening and passive case finding on the burden of TB in high-incidence prisons of Azerbaijan. Materials and methods All new and relapse TB cases notified in 01.01.2009-31.12.2015 were retrospectively included. Results 2,315 TB patients were identified in 19 prisons. Implementation of the rapid tests to the case finding algorithms lead to 3-, 10- and 5-fold decrease in the annual rates of the notified, smear-positive and RIF-resistant TB cases, respectively. After introduction of rapid tests into the screening algorithms, there were significant linear trends towards decrease in the notified (p=0.009), smear-positive (p=0.011) and RIF-resistant TB cases (p=0.02) with the annual rates of decrease (95% confidence interval (CI)) being -435 (-614; -255), -356 (-517; -195), and -99 (-160; -38), respectively. Utilization of rapid tests also significantly increased treatment success with first-line drugs among all cases, cases detected by mass screening and those, detected by passive case finding [adjusted odds ratio (aOR)=2.38, 95% CI:1.86-3.05, aOR=4.56, 95% CI:2.64-7.89 and aOR=2.60, 95% CI:1.81-3.75, respectively]. Conclusions Introduction of rapid tests into the screening lead to decline in the burden of TB and RIF-resistance, and improved outcomes of treatment with first-line drugs in prisons.http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1575-06202018000300111&lng=en&tlng=enStrainingTuberculosisPrisonsRadiographySurveys and Questionnaires
spellingShingle E Gurbanova
R Mehdiyev
K Blondal
A Altraja
Rapid tests reduce the burden of tuberculosis in Azerbaijan prisons: special emphasis on rifampicin-resistance
Revista Española de Sanidad Penitenciaria
Straining
Tuberculosis
Prisons
Radiography
Surveys and Questionnaires
title Rapid tests reduce the burden of tuberculosis in Azerbaijan prisons: special emphasis on rifampicin-resistance
title_full Rapid tests reduce the burden of tuberculosis in Azerbaijan prisons: special emphasis on rifampicin-resistance
title_fullStr Rapid tests reduce the burden of tuberculosis in Azerbaijan prisons: special emphasis on rifampicin-resistance
title_full_unstemmed Rapid tests reduce the burden of tuberculosis in Azerbaijan prisons: special emphasis on rifampicin-resistance
title_short Rapid tests reduce the burden of tuberculosis in Azerbaijan prisons: special emphasis on rifampicin-resistance
title_sort rapid tests reduce the burden of tuberculosis in azerbaijan prisons special emphasis on rifampicin resistance
topic Straining
Tuberculosis
Prisons
Radiography
Surveys and Questionnaires
url http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1575-06202018000300111&lng=en&tlng=en
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AT rmehdiyev rapidtestsreducetheburdenoftuberculosisinazerbaijanprisonsspecialemphasisonrifampicinresistance
AT kblondal rapidtestsreducetheburdenoftuberculosisinazerbaijanprisonsspecialemphasisonrifampicinresistance
AT aaltraja rapidtestsreducetheburdenoftuberculosisinazerbaijanprisonsspecialemphasisonrifampicinresistance