Rapid tests reduce the burden of tuberculosis in Azerbaijan prisons: special emphasis on rifampicin-resistance
ABSTRACT Aims To evaluate the impact of addition of rapid tests for tuberculosis (TB) to mass screening and passive case finding on the burden of TB in high-incidence prisons of Azerbaijan. Materials and methods All new and relapse TB cases notified in 01.01.2009-31.12.2015 were retrospectively in...
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Language: | English |
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Sociedad Española de Sanidad Penitenciaria
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Series: | Revista Española de Sanidad Penitenciaria |
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Online Access: | http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1575-06202018000300111&lng=en&tlng=en |
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author | E Gurbanova R Mehdiyev K Blondal A Altraja |
author_facet | E Gurbanova R Mehdiyev K Blondal A Altraja |
author_sort | E Gurbanova |
collection | DOAJ |
description | ABSTRACT Aims To evaluate the impact of addition of rapid tests for tuberculosis (TB) to mass screening and passive case finding on the burden of TB in high-incidence prisons of Azerbaijan. Materials and methods All new and relapse TB cases notified in 01.01.2009-31.12.2015 were retrospectively included. Results 2,315 TB patients were identified in 19 prisons. Implementation of the rapid tests to the case finding algorithms lead to 3-, 10- and 5-fold decrease in the annual rates of the notified, smear-positive and RIF-resistant TB cases, respectively. After introduction of rapid tests into the screening algorithms, there were significant linear trends towards decrease in the notified (p=0.009), smear-positive (p=0.011) and RIF-resistant TB cases (p=0.02) with the annual rates of decrease (95% confidence interval (CI)) being -435 (-614; -255), -356 (-517; -195), and -99 (-160; -38), respectively. Utilization of rapid tests also significantly increased treatment success with first-line drugs among all cases, cases detected by mass screening and those, detected by passive case finding [adjusted odds ratio (aOR)=2.38, 95% CI:1.86-3.05, aOR=4.56, 95% CI:2.64-7.89 and aOR=2.60, 95% CI:1.81-3.75, respectively]. Conclusions Introduction of rapid tests into the screening lead to decline in the burden of TB and RIF-resistance, and improved outcomes of treatment with first-line drugs in prisons. |
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id | doaj.art-51700686018a46bfba7b0af6c4d5e2bf |
institution | Directory Open Access Journal |
issn | 2013-6463 |
language | English |
last_indexed | 2024-12-20T02:42:35Z |
publisher | Sociedad Española de Sanidad Penitenciaria |
record_format | Article |
series | Revista Española de Sanidad Penitenciaria |
spelling | doaj.art-51700686018a46bfba7b0af6c4d5e2bf2022-12-21T19:56:17ZengSociedad Española de Sanidad PenitenciariaRevista Española de Sanidad Penitenciaria2013-6463203111120S1575-06202018000300111Rapid tests reduce the burden of tuberculosis in Azerbaijan prisons: special emphasis on rifampicin-resistanceE GurbanovaR MehdiyevK BlondalA AltrajaABSTRACT Aims To evaluate the impact of addition of rapid tests for tuberculosis (TB) to mass screening and passive case finding on the burden of TB in high-incidence prisons of Azerbaijan. Materials and methods All new and relapse TB cases notified in 01.01.2009-31.12.2015 were retrospectively included. Results 2,315 TB patients were identified in 19 prisons. Implementation of the rapid tests to the case finding algorithms lead to 3-, 10- and 5-fold decrease in the annual rates of the notified, smear-positive and RIF-resistant TB cases, respectively. After introduction of rapid tests into the screening algorithms, there were significant linear trends towards decrease in the notified (p=0.009), smear-positive (p=0.011) and RIF-resistant TB cases (p=0.02) with the annual rates of decrease (95% confidence interval (CI)) being -435 (-614; -255), -356 (-517; -195), and -99 (-160; -38), respectively. Utilization of rapid tests also significantly increased treatment success with first-line drugs among all cases, cases detected by mass screening and those, detected by passive case finding [adjusted odds ratio (aOR)=2.38, 95% CI:1.86-3.05, aOR=4.56, 95% CI:2.64-7.89 and aOR=2.60, 95% CI:1.81-3.75, respectively]. Conclusions Introduction of rapid tests into the screening lead to decline in the burden of TB and RIF-resistance, and improved outcomes of treatment with first-line drugs in prisons.http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1575-06202018000300111&lng=en&tlng=enStrainingTuberculosisPrisonsRadiographySurveys and Questionnaires |
spellingShingle | E Gurbanova R Mehdiyev K Blondal A Altraja Rapid tests reduce the burden of tuberculosis in Azerbaijan prisons: special emphasis on rifampicin-resistance Revista Española de Sanidad Penitenciaria Straining Tuberculosis Prisons Radiography Surveys and Questionnaires |
title | Rapid tests reduce the burden of tuberculosis in Azerbaijan prisons: special emphasis on rifampicin-resistance |
title_full | Rapid tests reduce the burden of tuberculosis in Azerbaijan prisons: special emphasis on rifampicin-resistance |
title_fullStr | Rapid tests reduce the burden of tuberculosis in Azerbaijan prisons: special emphasis on rifampicin-resistance |
title_full_unstemmed | Rapid tests reduce the burden of tuberculosis in Azerbaijan prisons: special emphasis on rifampicin-resistance |
title_short | Rapid tests reduce the burden of tuberculosis in Azerbaijan prisons: special emphasis on rifampicin-resistance |
title_sort | rapid tests reduce the burden of tuberculosis in azerbaijan prisons special emphasis on rifampicin resistance |
topic | Straining Tuberculosis Prisons Radiography Surveys and Questionnaires |
url | http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1575-06202018000300111&lng=en&tlng=en |
work_keys_str_mv | AT egurbanova rapidtestsreducetheburdenoftuberculosisinazerbaijanprisonsspecialemphasisonrifampicinresistance AT rmehdiyev rapidtestsreducetheburdenoftuberculosisinazerbaijanprisonsspecialemphasisonrifampicinresistance AT kblondal rapidtestsreducetheburdenoftuberculosisinazerbaijanprisonsspecialemphasisonrifampicinresistance AT aaltraja rapidtestsreducetheburdenoftuberculosisinazerbaijanprisonsspecialemphasisonrifampicinresistance |