Identification of AKR1B10 as a key gene in primary biliary cholangitis by integrated bioinformatics analysis and experimental validation

Identification of AKR1B10 as a key gene in primary biliary cholangitis by integrated bioinformatics analysis and experimental validation

Background: Primary biliary cholangitis (PBC) is a chronic autoimmune liver disease that eventually progresses to cirrhosis and hepatocellular carcinoma (HCC) in the absence of proper treatment. However, Gene expression and molecular mechanisms involved in the pathogenesis of PBC have not been compl...

Full description

Bibliographic Details
Main Authors: Huiwen Wang, Jian Zhang, Jinqing Liu, Yongfang Jiang, Lei Fu, Shifang Peng
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Molecular Biosciences
Subjects:
AKR1B10
primary biliary cholangitis
integrated bioinformatics
differentially expressed genes
hub genes
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1124956/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2023.1124956/full

Similar Items