The Mechanism of Polygonum Hydropiper L-Coptis Chinensis in the Treatment of Ulcerative Colitis Based on Network Pharmacology and Experimental Validation

The Mechanism of Polygonum Hydropiper L-Coptis Chinensis in the Treatment of Ulcerative Colitis Based on Network Pharmacology and Experimental Validation

Background: Polygonum hydropiper L (PH) was widely used to treat dysentery, gastroenteritis, diarrhea and other diseases. Coptis chinensis (CC) had the effects of clearing dampness-heat, purging fire, and detoxifying. Study confirmed that flavonoids in PH and alkaloids in CC alleviated inflammation...

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Bibliographic Details
Main Authors: Feifei Zhu, Yunyun Zhi, Yonghui Li, Haiyan Niu, Shouzhong Ren
Format: Article
Language:English
Published: IMR Press 2024-03-01
Series:Frontiers in Bioscience-Landmark
Subjects:
polygonum hydropiper l-coptis chinensis
ulcerative colitis
inflammatory response
nlrp3/caspase-1 signal pathway
proptosis
network pharmacology
Online Access:https://www.imrpress.com/journal/FBL/29/3/10.31083/j.fbl2903093

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https://www.imrpress.com/journal/FBL/29/3/10.31083/j.fbl2903093

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