Semisynthetic and SAR Studies of Amide Derivatives of Neocrotocembraneic Acid as Potential Antitumor Agents

A series of novel amide derivatives of cembranoid neocrotocembraneic acid were designed and synthesized. The antiproliferative activities of these derivatives were evaluated against three human tumor cell lines (the human cervical cancer cell line HeLa, chronic myeloid leukemia cell line K562 and le...

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Bibliographic Details
Main Authors: Hai Shang, Ling-Yu Li, Wei-Hua Cheng, Jun Luo, Hong-Wu Zhang, Zhong-Mei Zou
Format: Article
Language:English
Published: MDPI AG 2016-11-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/21/11/1581