Development of Protective Inflammation and Cell-Mediated Immunity against <named-content content-type="genus-species">Cryptococcus neoformans</named-content> after Exposure to Hyphal Mutants

ABSTRACT Morphological switch is tightly coupled with the pathogenesis of many dimorphic fungal pathogens. Cryptococcus neoformans, the major causative agent of cryptococcal meningitis, mostly presents as the yeast form but is capable of switching to the hyphal form. The filamentous form has long be...

Full description

Bibliographic Details
Main Authors: Bing Zhai, Karen L. Wozniak, Jorge Masso-Silva, Srijana Upadhyay, Camaron Hole, Amariliz Rivera, Floyd L. Wormley, Xiaorong Lin
Format: Article
Language:English
Published: American Society for Microbiology 2015-10-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.01433-15