A novel prognostic scoring model based on copper homeostasis and cuproptosis which indicates changes in tumor microenvironment and affects treatment response

A novel prognostic scoring model based on copper homeostasis and cuproptosis which indicates changes in tumor microenvironment and affects treatment response

Background: Intracellular copper homeostasis requires a complex system. It has shown considerable prospects for intervening in the tumor microenvironment (TME) by regulating copper homeostasis and provoking cuproptosis. Their relationship with hepatocellular carcinoma (HCC) remains elusive.Methods:...

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Bibliographic Details
Main Authors: Yun-Long Ma, Ya-Fei Yang, Han-Chao Wang, Chun-Cheng Yang, Lun-Jie Yan, Zi-Niu Ding, Bao-Wen Tian, Hui Liu, Jun-Shuai Xue, Cheng-Long Han, Si-Yu Tan, Jian-Guo Hong, Yu-Chuan Yan, Xin-Cheng Mao, Dong-Xu Wang, Tao Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Pharmacology
Subjects:
copper homeostasis
cuproptosis
hepatocellular carcinoma
prognostic model
tumor microenvironment
immunocytes
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1101749/full

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https://www.frontiersin.org/articles/10.3389/fphar.2023.1101749/full

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