Inhibitory effect of a tyrosine-fructose Maillard reaction product, 2,4-bis(<it>p</it>-hydroxyphenyl)-2-butenal on amyloid-β generation and inflammatory reactions via inhibition of NF-κB and STAT3 activation in cultured astrocytes and microglial BV-2 cells

Inhibitory effect of a tyrosine-fructose Maillard reaction product, 2,4-bis(<it>p</it>-hydroxyphenyl)-2-butenal on amyloid-β generation and inflammatory reactions via inhibition of NF-κB and STAT3 activation in cultured astrocytes and microglial BV-2 cells

<p>Abstract</p> <p>Background</p> <p>Amyloidogenesis is linked to neuroinflammation. The tyrosine-fructose Maillard reaction product, 2,4-bis(<it>p</it>-hydroxyphenyl)-2-butenal, possesses anti-inflammatory properties in cultured macrophages, and in an arthr...

Full description

Bibliographic Details
Main Authors: Choi Im Seup, Choi Dong-Young, Lee Young-Jung, Han Jin-Yi, Jeong Heon-Sang, Han Sang Bae, Oh Ki-Wan, Hong Jin Tae
Format: Article
Language:English
Published: BMC 2011-10-01
Series:Journal of Neuroinflammation
Subjects:
2,4-bis(<it>p</it>-hydroxyphenyl)-2-butenal
NF-κB
STAT3
neuroinflammation
amyloidogenesis
Online Access:http://www.jneuroinflammation.com/content/8/1/132

Internet

http://www.jneuroinflammation.com/content/8/1/132

Similar Items