Cyclocarya paliurus Triterpenoids Improve Diabetes-Induced Hepatic Inflammation via the Rho-Kinase-Dependent Pathway

Cyclocarya paliurus Triterpenoids Improve Diabetes-Induced Hepatic Inflammation via the Rho-Kinase-Dependent Pathway

This study aimed to assess the effects of triterpene extract of Cyclocarya paliurus (Batal.) Iljinskaja (CPT) on diabetes-induced hepatic inflammation and to unveil the underlying mechanisms. Diabetes in db/db mice was alleviated after CPT administration, as assessed by the oral glucose tolerance te...

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Bibliographic Details
Main Authors: Cuihua Jiang, Yiting Wang, Qiaomei Jin, Dongjian Zhang, Meng Gao, Nan Yao, Zhiqi Yin, Jian Zhang, Shiping Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Pharmacology
Subjects:
Cyclocarya paliurus
triterpene
diabetes mellitus
hepatic inflammation
ROCK
NF-κB
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00811/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.00811/full

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