Concentration-dependent enantioselective transport of chiral timolol maleate across hairless mice skin upon using various concentrations of chiral terpene enhancer (DLimonene)

The objective of the present study was to examine the relationship between different concentrations of the chiral enhancer D-Limonene (D-LM) on the solubility of individual enantiomers and racemate Timolol maleate (TM). The preferential improvement of D-LM on S-TM, R-TM, and racemate transported acr...

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Bibliographic Details
Main Author: Mohsen I. Afouna
Format: Article
Language:English
Published: International Pharmaceutical Excipients Council 2016-11-01
Series:Journal of Excipients and Food Chemicals
Online Access:https://jefc.scholasticahq.com/article/1008-concentration-dependent-enantioselective-transport-of-chiral-timolol-maleate-across-hairless-mice-skin-upon-using-various-concentrations-of-chiral-ter