Alternans in genetically modified Langendorff-perfused murine hearts modeling catecholaminergic polymorphic ventricular tachycardia

Alternans in genetically modified Langendorff-perfused murine hearts modeling catecholaminergic polymorphic ventricular tachycardia

The relationship between alternans and arrhythmogenicity was studied in genetically modified murine hearts modeling catecholaminergic polymorphic ventricular tachycardia (CPVT) during Langendorff perfusion, before and after treatment with catecholamines and a β-adrenergic antagonist. Hetero...

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Bibliographic Details
Main Authors: Ian N Sabir, Nan Ma, Victoria Jones, Catharine A Goddard, Yanmin Zhang, Asli Kalin, Andrew Grace, Christopher Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2010-10-01
Series:Frontiers in Physiology
Subjects:
Brugada Syndrome
Catecholaminergic polymorphic ventricular tachycardia
arrhythmia
Sudden cardiac death
alternans
ryanodine Receptor
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2010.00126/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2010.00126/full

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