S. aureus hemolysins, bi-component leukocidins and cytolytic peptides: a redundant arsenal of membrane-damaging virulence factors?

One key aspect of S. aureus virulence lies in its ability to target the host cell membrane with a large number of membrane-damaging toxins and peptides. In this review, we describe the hemolysins, the bi-component leukocidins, which include the Panton Valentine Leukocidin, LukAB/GH, LukED and the cy...

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Bibliographic Details
Main Authors: Francois eVandenesch, Gérard eLina, Thomas eHenry
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-02-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2012.00012/full