Differences among epitopes recognized by neutralizing antibodies induced by SARS-CoV-2 infection or COVID-19 vaccination

Differences among epitopes recognized by neutralizing antibodies induced by SARS-CoV-2 infection or COVID-19 vaccination

Summary: SARS-CoV-2 has gradually acquired amino acid substitutions in its S protein that reduce the potency of neutralizing antibodies, leading to decreased vaccine efficacy. Here, we attempted to obtain mutant viruses by passaging SARS-CoV-2 in the presence of plasma samples from convalescent pati...

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Bibliographic Details
Main Authors: Shinya Yamamoto, Seiya Yamayoshi, Mutsumi Ito, Yuko Sakai-Tagawa, Ichiro Nakachi, Rie Baba, Shigenobu Kamimoto, Takayuki Ogura, Shigehiro Hagiwara, Hideaki Kato, Hideaki Nakajima, Yoshifumi Uwamino, Kazuma Yagi, Norio Sugaya, Hiroyuki Nagai, Makoto Saito, Eisuke Adachi, Michiko Koga, Takeya Tsutsumi, Calvin Duong, Moe Okuda, Jurika Murakami, Yuri Furusawa, Michiko Ujie, Kiyoko Iwatsuki-Horimoto, Hiroshi Yotsuyanagi, Yoshihiro Kawaoka
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:iScience
Subjects:
Immunology
Virology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223012853

Internet

http://www.sciencedirect.com/science/article/pii/S2589004223012853

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