Ferroptosis-related factors in the substantia nigra are associated with Parkinson’s disease

Abstract Ferroptosis is an iron-dependent, lipid peroxidation-driven cell death pathway, while Parkinson’s disease (PD) patients exhibit iron deposition and lipid peroxidation in the brain. Thus, the features of ferroptosis highly overlap with the pathophysiological features of PD. Despite this supe...

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Bibliographic Details
Main Authors: Lei Liu, Yange Cui, Yan-Zhong Chang, Peng Yu
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-42574-4