Human retinal endothelial cells express functional interleukin-6 receptor

Abstract Background Interleukin (IL)-6 is an inflammatory cytokine present in the eye during non-infectious uveitis, where it contributes to the progression of inflammation. There are two major IL-6 signaling pathways: classic signaling and trans-signaling. Classic signaling requires cellular expres...

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Bibliographic Details
Main Authors: Lisia Barros Ferreira, Liam M. Ashander, Binoy Appukuttan, Yuefang Ma, Keryn A. Williams, Giles Best, Justine R. Smith
Format: Article
Language:English
Published: SpringerOpen 2023-04-01
Series:Journal of Ophthalmic Inflammation and Infection
Subjects:
Online Access:https://doi.org/10.1186/s12348-023-00341-6