Extracellular matrix and dermal nerve growth factor dysregulation in prurigo nodularis compared to atopic dermatitis

Extracellular matrix and dermal nerve growth factor dysregulation in prurigo nodularis compared to atopic dermatitis

Prurigo nodularis (PN) is a chronic, pruritic, inflammatory skin disease characterized by hyperkeratotic nodules on the trunk and extremities. While there is growing research on the immunological basis of PN, the neuropathic and structural components of PN lesions are unknown. This study examines th...

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Bibliographic Details
Main Authors: Junwen Deng, Varsha Parthasarathy, Melika Marani, Zachary Bordeaux, Kevin Lee, Chi Trinh, Hannah L. Cornman, Anusha Kambala, Thomas Pritchard, Shihua Chen, Nishadh Sutaria, Olusola O. Oladipo, Madan M. Kwatra, Martin P. Alphonse, Shawn G. Kwatra
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Medicine
Subjects:
prurigo nodularis
atopic dermatitis
pruritus
transcriptome
immune
nerve growth factor
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.1022889/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2022.1022889/full

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