Deacetylation of FOXP1 by HDAC7 potentiates self-renewal of mesenchymal stem cells

Deacetylation of FOXP1 by HDAC7 potentiates self-renewal of mesenchymal stem cells

Abstract Background Mesenchymal stem cells (MSCs) are widely used in a variety of tissue regeneration and clinical trials due to their multiple differentiation potency. However, it remains challenging to maintain their replicative capability during in vitro passaging while preventing their premature...

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Bibliographic Details
Main Authors: Shifeng Ling, Tienan Chen, Shaojiao Wang, Wei Zhang, Rujiang Zhou, Xuechun Xia, Zhengju Yao, Ying Fan, Song Ning, Jiayin Liu, Lianju Qin, Haley O. Tucker, Niansong Wang, Xizhi Guo
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stem cells
Self-renewal
Deacetylation
FOXP1
HDAC7
Online Access:https://doi.org/10.1186/s13287-023-03376-7

Internet

https://doi.org/10.1186/s13287-023-03376-7

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