Frailty in randomised controlled trials for dementia or mild cognitive impairment measured via the frailty index: prevalence and prediction of serious adverse events and attrition

Frailty in randomised controlled trials for dementia or mild cognitive impairment measured via the frailty index: prevalence and prediction of serious adverse events and attrition

Abstract Background Frailty and dementia have a bidirectional relationship. However, frailty is rarely reported in clinical trials for dementia and mild cognitive impairment (MCI) which limits assessment of trial applicability. This study aimed to use a frailty index (FI)—a cumulative deficit model...

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Bibliographic Details
Main Authors: Heather Wightman, Terry J. Quinn, Frances S. Mair, Jim Lewsey, David A. McAllister, Peter Hanlon
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Alzheimer’s Research & Therapy
Subjects:
Frailty
Dementia
Cognitive impairment
Randomised controlled trials
Online Access:https://doi.org/10.1186/s13195-023-01260-3

Internet

https://doi.org/10.1186/s13195-023-01260-3

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