IGF-1/IGFBP-1 increases blastocyst formation and total blastocyst cell number in mouse embryo culture and facilitates the establishment of a stem-cell line

<p>Abstract</p> <p>Background</p> <p>Apoptosis occurs frequently for blastocysts cultured <it>in vitro</it>, where conditions are suboptimal to those found in the natural environment. Insulin-like growth factor-1 (IGF-1) plays an important role in preventing...

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Bibliographic Details
Main Authors: Hsu Teng-Tsao, Gong Kun-Bing, Yen Jui-Mei, Lin Ta-Chin, Chen Lih-Ren
Format: Article
Language:English
Published: BMC 2003-09-01
Series:BMC Cell Biology
Online Access:http://www.biomedcentral.com/1471-2121/4/14