CD4 T cells specific for factor VIII are present at high frequency in healthy donors and comprise naïve and memory cells
Abstract: We investigated the frequency and subset origin of circulating factor VIII (FVIII)–specific CD4 T cells in healthy donors. Total CD4 T cells and purified CD4 T-cell subsets were stimulated with FVIII-loaded autologous dendritic cells and challenged for specificity in interferon-γ enzyme-li...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2017-09-01
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| Series: | Blood Advances |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S247395292030327X |