Brief report: Assessment of mucosal barrier integrity using serological biomarkers in preclinical stages of rheumatoid arthritis

Brief report: Assessment of mucosal barrier integrity using serological biomarkers in preclinical stages of rheumatoid arthritis

BackgroundThe pathogenesis of rheumatoid arthritis (RA) is believed to initiate at mucosal sites. The so-called ‘mucosal origin hypothesis of RA’ postulates an increased intestinal permeability before disease onset. Several biomarkers, including lipopolysaccharide binding protein (LBP) and intestina...

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Bibliographic Details
Main Authors: Benoît Thomas P. Gilbert, Céline Lamacchia, Lena Amend, Till Strowig, Emiliana Rodriguez, Gaby Palmer, Axel Finckh
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Immunology
Subjects:
rheumatoid arthritis
gut permeability
intestinal inflammation
autoimmunity
biomarker
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1117742/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1117742/full

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