Phosphatidylserine synthase plays an essential role in glia and affects development, as well as the maintenance of neuronal function

Summary: Phosphatidylserine (PS) is an integral component of eukaryotic cell membranes and organelles. The Drosophila genome contains a single PS synthase (PSS)-encoding gene (Pss) homologous to mammalian PSSs. Flies with Pss loss-of-function alleles show a reduced life span, increased bang sensitiv...

Full description

Bibliographic Details
Main Authors: Ye-Jin Park, Sungkyung Kim, Hyeon-Pyo Shim, Jae H. Park, Gyunghee Lee, Tae-Yeop Kim, Min-Cue Jo, Ah-Young Kwon, Mihwa Lee, Seongjae Lee, Jiwon Yeo, Hyung-Lok Chung, Hugo J. Bellen, Seung-Hae Kwon, Sang-Hak Jeon
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221008671