Mice engineered to mimic a common Val66Met polymorphism in the BDNF gene show greater sensitivity to reversal in environmental contingencies

• A common human polymorphism in the gene that encodes brain derived neurotrophic factor (BDNF), Val66Met, is considered a marker of vulnerability for mental health issues and has been associated with cognitive impairment. An alternate framework has been proposed in which “risk alleles” are reinterp...

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Bibliographic Details
Main Authors: Angela Vandenberg, Wan Chen Lin, Lung-Hao Tai, Dorit Ron, Linda Wilbrecht
Format: Article
Language:English
Published: Elsevier 2018-11-01
Series:Developmental Cognitive Neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S1878929317302220