Mice engineered to mimic a common Val66Met polymorphism in the BDNF gene show greater sensitivity to reversal in environmental contingencies
• A common human polymorphism in the gene that encodes brain derived neurotrophic factor (BDNF), Val66Met, is considered a marker of vulnerability for mental health issues and has been associated with cognitive impairment. An alternate framework has been proposed in which “risk alleles” are reinterp...
Main Authors: | Angela Vandenberg, Wan Chen Lin, Lung-Hao Tai, Dorit Ron, Linda Wilbrecht |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-11-01
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Series: | Developmental Cognitive Neuroscience |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1878929317302220 |
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