| Summary: | ObjectiveTo estimate the global prevalence and concentration of deoxynivalenol （DON）， aflatoxins （AFs）， zearalenone （ZEN）， nivalenol （NIV）， T-2 toxin （T2）， HT-2 toxin （HT2）， ochratoxin A （OTA）， fumonisins （FBs）， alternariol （AOH）， alternariol monomethyl ether （AME）， tentoxin （TEN） and tenuazonic acid （TeA） in wheat and wheat-based products via Meta-analysis.MethodsThe databases include PubMed， Web of Science， CNKI and WANFANG database.ResultsA total of 69 eligible studies were included in this study， related to 22，308 samples. The global pooled prevalence of mycotoxins in wheat and wheat-based products was 58% （95%CI： 51%-66%）， which mainly were TeA （99%）， TEN （88%）， DON （85%）， AFs （57%）， ZEN （42%）， T2 （39%）， AOH （30%）， AME （29%）， NIV （28%）， HT2 （25%）， OTA （21%） and FBs （16%）. The global pooled concentration of mycotoxins in wheat and wheat-based products was 32.80 μg/kg （95%CI： 24.96-43.10 μg/kg）. DON showed the highest concentration （317.53 μg/kg）， followed by TeA （117.37 μg/kg）， FBs （45.09 μg/kg）. The co-occurrence rate of DON-ZEN was 11.0%, 14.0% and 26.7%, TeA-TEN was 16.2%, TeA-TEN-AME was 14.3% and TeA-TEN-AOH-AME was 19.5%, respectively.ConclusionWheat and wheat-based products showed different characteristics of mycotoxin contamination in different countries or regions, and the co-occurrence rate of more than one mycotoxin in wheat and wheat-based products was high, which should be paid attention to in the combined exposure assessment.
|
|---|