Estimating axon radius using diffusion-relaxation MRI: calibrating a surface-based relaxation model with histology

Estimating axon radius using diffusion-relaxation MRI: calibrating a surface-based relaxation model with histology

Axon radius is a potential biomarker for brain diseases and a crucial tissue microstructure parameter that determines the speed of action potentials. Diffusion MRI (dMRI) allows non-invasive estimation of axon radius, but accurately estimating the radius of axons in the human brain is challenging. M...

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Bibliographic Details
Main Authors: Muhamed Barakovic, Marco Pizzolato, Chantal M. W. Tax, Umesh Rudrapatna, Stefano Magon, Tim B. Dyrby, Cristina Granziera, Jean-Philippe Thiran, Derek K. Jones, Erick J. Canales-Rodríguez
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Neuroscience
Subjects:
brain
axon radius
diffusion MRI
T2 relaxation
T1 relaxation
histology
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2023.1209521/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2023.1209521/full

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