Gap Junctions and Hemichannels Composed of Connexins and Pannexins Mediate the Secondary Brain Injury Following Intracerebral Hemorrhage

Gap Junctions and Hemichannels Composed of Connexins and Pannexins Mediate the Secondary Brain Injury Following Intracerebral Hemorrhage

Intracerebral hemorrhage (ICH) is a devastating disease with high mortality and morbidity; the mortality rate ranges from 40% at 1 month to 54% at 1 year; only 12–39% achieve good outcomes and functional independence. ICH affects nearly 2 million patients worldwide annually. In ICH development, the...

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Bibliographic Details
Main Authors: Yan Zhang, Suliman Khan, Yang Liu, Rabeea Siddique, Ruiyi Zhang, Voon Wee Yong, Mengzhou Xue
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Biology
Subjects:
intracerebral hemorrhage
secondary brain injury
pannexin
hemichannel
inflammation
oxidative stress
Online Access:https://www.mdpi.com/2079-7737/11/1/27

Internet

https://www.mdpi.com/2079-7737/11/1/27

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