Estimating individual exposure to malaria using local prevalence of malaria infection in the field.

BACKGROUND:Heterogeneity in malaria exposure complicates survival analyses of vaccine efficacy trials and confounds the association between immune correlates of protection and malaria infection in longitudinal studies. Analysis may be facilitated by taking into account the variability in individual...

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Bibliographic Details
Main Authors: Ally Olotu, Gregory Fegan, Juliana Wambua, George Nyangweso, Edna Ogada, Chris Drakeley, Kevin Marsh, Philip Bejon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3315550?pdf=render