Evolution of two distinct variable lymphocyte receptors in lampreys: VLRD and VLRE

Evolution of two distinct variable lymphocyte receptors in lampreys: VLRD and VLRE

Summary: Jawless vertebrates possess an alternative adaptive immune system in which antigens are recognized by variable lymphocyte receptors (VLRs) generated by combinatorial assembly of leucine-rich repeat (LRR) cassettes. Three types of receptors, VLRA, VLRB, and VLRC, have been previously identif...

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Bibliographic Details
Main Authors: Sabyasachi Das, Thomas Boehm, Stephen J. Holland, Jonathan P. Rast, Francisco Fontenla-Iglesias, Ryo Morimoto, J. Gerardo Valadez, Ryan D. Heimroth, Masayuki Hirano, Max D. Cooper
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Cell Reports
Subjects:
CP: Immunology
CP: Genomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723009440

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http://www.sciencedirect.com/science/article/pii/S2211124723009440

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