Evolution of two distinct variable lymphocyte receptors in lampreys: VLRD and VLRE
Summary: Jawless vertebrates possess an alternative adaptive immune system in which antigens are recognized by variable lymphocyte receptors (VLRs) generated by combinatorial assembly of leucine-rich repeat (LRR) cassettes. Three types of receptors, VLRA, VLRB, and VLRC, have been previously identif...
Main Authors: | Sabyasachi Das, Thomas Boehm, Stephen J. Holland, Jonathan P. Rast, Francisco Fontenla-Iglesias, Ryo Morimoto, J. Gerardo Valadez, Ryan D. Heimroth, Masayuki Hirano, Max D. Cooper |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-08-01
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Series: | Cell Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124723009440 |
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