Human Mesenchymal Stem Cells Are Susceptible to Lysis by CD8 T Cells and NK Cells

There is growing interest in the use of mesenchymal stem cells (MSCs) to improve the outcome of organ transplantation. The immunogenicity of MSCs is, however, unclear and is important for the efficacy of MSC therapy and for potential sensitization against donor antigens. We investigated the suscepti...

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Bibliographic Details
Main Authors: Meindert J. Crop, Sander S. Korevaar, Ronella De Kuiper, Jan N. M. Ijzermans, Nicole M. Van Besouw, Carla C. Baan, Willem Weimar, Martin J. Hoogduijn Ph.D.
Format: Article
Language:English
Published: SAGE Publishing 2011-11-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368910X564076