Functional validation of putative toxin-antitoxin genes from the Gram-positive pathogen Streptococcus pneumoniae: phd-doc is the fourth bona-fide operon

Bacterial toxin-antitoxin (TAs) loci usually consist of two genes organized as an operon, where their products are bound together and inert under normal conditions. However, under stressful circumstances the antitoxin, which is more labile, will be degraded more rapidly, thereby unleashing its cogna...

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Bibliographic Details
Main Authors: Wai Ting eChan, Chew Chieng eYeo, Ewa eSadowy, Manuel eEspinosa
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-12-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00677/full