Antibody Focusing to Conserved Sites of Vulnerability: The Immunological Pathways for ‘Universal’ Influenza Vaccines

Influenza virus remains a serious public health burden due to ongoing viral evolution. Vaccination remains the best measure of prophylaxis, yet current seasonal vaccines elicit strain-specific neutralizing responses that favor the hypervariable epitopes on the virus. This necessitates yearly reformu...

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Bibliographic Details
Main Authors: Maya Sangesland, Daniel Lingwood
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/9/2/125