Anti-Inflammatory Effects of the Iron Chelator, DIBI, in Experimental Acute Lung Injury

Anti-Inflammatory Effects of the Iron Chelator, DIBI, in Experimental Acute Lung Injury

Iron plays a critical role in the immune response to inflammation and infection due to its role in the catalysis of reactive oxygen species (ROS) through the Haber-Weiss and Fenton reactions. However, ROS overproduction can be harmful and damage healthy cells. Therefore, iron chelation represents an...

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Bibliographic Details
Main Authors: Christian Lehmann, Nazli Alizadeh-Tabrizi, Stefan Hall, Sufyan Faridi, Irene Euodia, Bruce Holbein, Juan Zhou, Valerie Chappe
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Molecules
Subjects:
acute lung injury
ARDS
cytokine storm
ROS
iron chelation
microcirculation
Online Access:https://www.mdpi.com/1420-3049/27/13/4036

Internet

https://www.mdpi.com/1420-3049/27/13/4036

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