The role of cytoreductive nephrectomy in metastatic renal cell carcinoma in immune-oncology era (SEVURO-CN): study protocol for a multi-center, prospective, randomized trial

The role of cytoreductive nephrectomy in metastatic renal cell carcinoma in immune-oncology era (SEVURO-CN): study protocol for a multi-center, prospective, randomized trial

Abstract Background The role of cytoreductive nephrectomy (CN) in the treatment of metastatic renal cell carcinoma (mRCC) remains unclear in the immuno-oncology (IO) era. The results of two randomized trials, CARMENA and SURTIME, questioned the role and timing of CN. However, despite the latest adva...

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Bibliographic Details
Main Authors: Jee Soo Park, Jongchan Kim, Jinhyung Jeon, Jongsoo Lee, Won Sik Jang, Seung Hwan Lee, Woong Kyu Han, Young Deuk Choi, Kyo Chul Koo, Kang Su Cho, Byung Ha Chung, Won Sik Ham
Format: Article
Language:English
Published: BMC 2024-07-01
Series:Trials
Subjects:
Renal cell carcinoma
Cytoreductive nephrectomy
Ipilimumab
Nivolumab
Immune checkpoint inhibitors
Kidney neoplasms
Online Access:https://doi.org/10.1186/s13063-024-08234-2

Internet

https://doi.org/10.1186/s13063-024-08234-2

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