Self-Assembling Lectin Nano-Block Oligomers Enhance Binding Avidity to Glycans

Self-Assembling Lectin Nano-Block Oligomers Enhance Binding Avidity to Glycans

Lectins, carbohydrate-binding proteins, are attractive biomolecules for medical and biotechnological applications. Many lectins have multiple carbohydrate recognition domains (CRDs) and strongly bind to specific glycans through multivalent binding effect. In our previous study, protein nano-building...

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Bibliographic Details
Main Authors: Shin Irumagawa, Keiko Hiemori, Sayoko Saito, Hiroaki Tateno, Ryoichi Arai
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:International Journal of Molecular Sciences
Subjects:
artificial protein
avidity
fusion protein
lectin engineering
multivalent binding effect
protein complex design
Online Access:https://www.mdpi.com/1422-0067/23/2/676

Internet

https://www.mdpi.com/1422-0067/23/2/676

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