Aspirin Attenuates Cardiac Allograft Rejection by Inhibiting the Maturation of Dendritic Cells via the NF-κB Signaling Pathway

Aspirin Attenuates Cardiac Allograft Rejection by Inhibiting the Maturation of Dendritic Cells via the NF-κB Signaling Pathway

Background: Dendritic cells (DCs) serve as an important part of the immune system and play a dual role in immune response. Mature DCs can initiate immune response, while immature or semi-mature DCs induce immune hyporesponsiveness or tolerance. Previous studies have shown that aspirin can effectivel...

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Bibliographic Details
Main Authors: Xi Zhang, Aie Chang, Yanqiang Zou, Heng Xu, Jikai Cui, Zhang Chen, Yuan Li, Yifan Du, Jie Wu, Jizhang Yu, Xinling Du
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Pharmacology
Subjects:
aspirin
heart transplantation
dendritic cells
allograft rejection
NF-κB
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.706748/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.706748/full

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