Increased expression of interleukin-1β in triglyceride-induced macrophage cell death is mediated by p38 MAP kinase

Increased expression of interleukin-1β in triglyceride-induced macrophage cell death is mediated by p38 MAP kinase

Triglycerides (TG) are implicated in the development ofatherosclerosis through formation of foam cells and induction ofmacrophage cell death. In this study, we report that addition ofexogenous TG induced cell death in phorbol 12-myristate13-acetate-differentiated THP-1 human macrophages. TGtreatment...

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Bibliographic Details
Main Author: Ho Joong Sung1,#, Sin Jee Son2,#, Seung-ju Yang3, Ki-Jong Rhee2 & Yoon Suk Kim2,*
Format: Article
Language:English
Published: Korean Society for Biochemistry and Molecular Biology 2012-07-01
Series:BMB Reports
Subjects:
Cell death
IL-1β
Macrophage
p38 MAP kinase
Triglyceride
Online Access:http://www.jbmb.or.kr/jbmb/pdf.php?data=MTMwMTIyMTdAcGRmX3JhaW50cmFjZV9sZWV5c0AlNUI0NS03JTVEMTIwNzI2MDgyMV8lMjg0MTQtNDE4JTI5Qk1CXzEyLTA4OC5wZGY=

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http://www.jbmb.or.kr/jbmb/pdf.php?data=MTMwMTIyMTdAcGRmX3JhaW50cmFjZV9sZWV5c0AlNUI0NS03JTVEMTIwNzI2MDgyMV8lMjg0MTQtNDE4JTI5Qk1CXzEyLTA4OC5wZGY=

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