Alternate typhoid toxin assembly evolved independently in the two Salmonella species

ABSTRACTAB5-type toxins are a diverse family of protein toxins composed of an enzymatic active (A) subunit and a pentameric delivery (B) subunit. Salmonella enterica serovar Typhi’s typhoid toxin features two A subunits, CdtB and PltA, in complex with the B subunit PltB. Recently, it was shown that...

Full description

Bibliographic Details
Main Authors: Antonio J. Chemello, Casey C. Fowler
Format: Article
Language:English
Published: American Society for Microbiology 2024-04-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mbio.03403-23