Induction of the CLOCK gene by E2-ERα signaling promotes the proliferation of breast cancer cells.

Induction of the CLOCK gene by E2-ERα signaling promotes the proliferation of breast cancer cells.

Growing genetic and epidemiological evidence suggests a direct connection between the disruption of circadian rhythm and breast cancer. Moreover, the expression of several molecular components constituting the circadian clock machinery has been found to be modulated by estrogen-estrogen receptor α (...

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Bibliographic Details
Main Authors: Liyun Xiao, Alan K Chang, Ming-Xi Zang, Hailian Bi, Shujing Li, Miao Wang, Xinrong Xing, Huijian Wu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0095878&type=printable

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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0095878&type=printable

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