Whole Genome Transcriptomic Analysis of Ovary Granulosa Cells Revealed an Anti-Apoptosis Regulatory Gene DLGAP5 in Polycystic Ovary Syndrome

Whole Genome Transcriptomic Analysis of Ovary Granulosa Cells Revealed an Anti-Apoptosis Regulatory Gene DLGAP5 in Polycystic Ovary Syndrome

The mechanisms underlining pathogenesis of polycystic ovary syndrome (PCOS) remain largely unknown. Dysfunction of ovarian granulosa cells plays an important role. The present study performed the lncRNA and mRNA profiling by whole genome transcriptomic sequencing of ovary granulosa cells from women...

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Bibliographic Details
Main Authors: Yan Deng, Hu Li, Yi Song, Juan Cen, Yuying Zhang, Yi Sui, Dexuan Cui, Tin Chiu Li, Yan Xu, Chi Chiu Wang, Pui Wah Jacqueline Chung, Tao Tang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Endocrinology
Subjects:
PCOS
transcriptomic analysis
ovary granulosa cells
DLGAP5
apoptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.781149/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.781149/full

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