Mechanism of Action and Therapeutic Potential of the β-Hairpin Antimicrobial Peptide Capitellacin from the Marine Polychaeta <i>Capitella teleta</i>

Mechanism of Action and Therapeutic Potential of the β-Hairpin Antimicrobial Peptide Capitellacin from the Marine Polychaeta <i>Capitella teleta</i>

Among the most potent and proteolytically resistant antimicrobial peptides (AMPs) of animal origin are molecules forming a β-hairpin structure stabilized by disulfide bonds. In this study, we investigated the mechanism of action and therapeutic potential of the β-hairpin AMP from the marine polychae...

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Bibliographic Details
Main Authors: Victoria N. Safronova, Pavel V. Panteleev, Stanislav V. Sukhanov, Ilia Y. Toropygin, Ilia A. Bolosov, Tatiana V. Ovchinnikova
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Marine Drugs
Subjects:
antimicrobial peptide
capitellacin
site-directed mutagenesis
antimicrobial resistance
antibiofilm activity
Online Access:https://www.mdpi.com/1660-3397/20/3/167

Internet

https://www.mdpi.com/1660-3397/20/3/167

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