Global connectivity in genome-scale metabolic networks revealed by comprehensive FBA-based pathway analysis

Abstract Background Graph-based analysis (GBA) of genome-scale metabolic networks has revealed system-level structures such as the bow-tie connectivity that describes the overall mass flow in a network. However, many pathways obtained by GBA are biologically impossible, making it difficult to study...

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Bibliographic Details
Main Authors: Yajie Gao, Qianqian Yuan, Zhitao Mao, Hao Liu, Hongwu Ma
Format: Article
Language:English
Published: BMC 2021-10-01
Series:BMC Microbiology
Subjects:
Online Access:https://doi.org/10.1186/s12866-021-02357-1