Efficacy of matrilin-3-primed adipose-derived mesenchymal stem cell spheroids in a rabbit model of disc degeneration

Efficacy of matrilin-3-primed adipose-derived mesenchymal stem cell spheroids in a rabbit model of disc degeneration

Abstract Background Chronic low back pain is a prevalent disability, often caused by intervertebral disc (IVD) degeneration. Mesenchymal stem cell (MSC) therapy could be a safe and feasible option for repairing the degenerated disc. However, for successful translation to the clinic, various challeng...

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Bibliographic Details
Main Authors: Manjunatha S. Muttigi, Byoung Ju Kim, Hemant Kumar, Sunghyun Park, Un Yong Choi, Inbo Han, Hansoo Park, Soo-Hong Lee
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Stem Cell Research & Therapy
Subjects:
Intervertebral disc
Degeneration
Mesenchymal stem cell
Matrilin-3
Priming
Spheroid
Online Access:http://link.springer.com/article/10.1186/s13287-020-01862-w

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http://link.springer.com/article/10.1186/s13287-020-01862-w

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