Evidence for the existence of facilitatory interactions between the dopamine D2 receptor and the oxytocin receptor in the amygdala of the rat. Relevance for anxiolytic actions

Evidence for the existence of facilitatory interactions between the dopamine D2 receptor and the oxytocin receptor in the amygdala of the rat. Relevance for anxiolytic actions

Introduction: The amygdala is a limbic region of high value for understanding anxiety and its treatment. Dopamine D2 receptors (D2Rs) and oxytocin receptors (OXTRs) have both been shown to participate in modulating anxiety involving effects in the amygdala. The goal is to understand if D2R–OXTR hete...

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Bibliographic Details
Main Authors: Juan Carlos Hernández-Mondragón, Dexter A. Hernández-Hernández, Minerva Crespo-Ramírez, Oscar Prospero-García, Luisa Rocha-Arrieta, Kjell Fuxe, Dasiel O. Borroto-Escuela, Miguel Perez de la Mora
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Pharmacology
Subjects:
G protein-coupled receptors
oligomerization
heteroreceptor complexes
oxytocin receptor
dopamine D2 receptor
amygdala
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1251922/full

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https://www.frontiersin.org/articles/10.3389/fphar.2023.1251922/full

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