Roles of the Dbl family of RhoGEFs in mechanotransduction – a review

Rho guanine nucleotide exchange factors (RhoGEFs) comprise a wide range of proteins with a common domain responsible for the activation of the Rho family of small GTPases and various domains in other regions. The evolutionary divergence of RhoGEFs enables actin cytoskeletal reorganization, leading t...

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Bibliographic Details
Main Authors: Kazumasa Ohashi, Aoi Kunitomi, Shuhei Chiba, Kensaku Mizuno
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2024.1485725/full