In vitro optimization of crushed drug-sensitive antituberculosis medication when administered via a nasogastric tube

In vitro optimization of crushed drug-sensitive antituberculosis medication when administered via a nasogastric tube

ABSTRACT In low-resource settings, access to intravenous formulations of antituberculosis drugs is lacking or absent. Thus, critically ill patients with tuberculosis (TB) are often treated with readily available tablets which are crushed, mixed with water, and administered via a nasogastric tube (NG...

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Bibliographic Details
Main Authors: Cassius M. Phogole, Jocelyn de Jong, Usha Lalla, Eric Decloedt, Tracy Kellermann
Format: Article
Language:English
Published: American Society for Microbiology 2024-01-01
Series:Microbiology Spectrum
Subjects:
HPLC
antituberculosis drugs
crushing
nasogastric tube
ascorbic acid
bioavailability
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02876-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.02876-23

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