CERKL attenuates blue light-induced oxidative stress in human retinal pigment epithelial cells by activating the SIRT1/E2F1 axis

AIM:To investigate whether ceramide kinase-like protein(CERKL)alleviates oxidative stress injury of retinal pigment epithelial(RPE)cells induced by blue light via activating the silent information regulator 1(SIRT1)/E2F transcription factor 1(E2F1)axis. METHODS:Cultured human retinal pigment epithel...

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Bibliographic Details
Main Authors: Hai-Rong Zhuang, Zi-Dong Wu, Xue-Hong Chen, Cheng-Jun Li
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2022-08-01
Series:Guoji Yanke Zazhi
Subjects:
Online Access:http://ies.ijo.cn/cn_publish/2022/8/202208002.pdf