BAP1 in cancer: epigenetic stability and genome integrity
Abstract Mutations in BAP1 have been identified in a hereditary cancer predisposition syndrome and in sporadic tumours. Individuals carrying familiar BAP1 monoallelic mutations display hypersusceptibility to exposure-associated cancers, such as asbestos-driven mesothelioma, thus BAP1 status has been...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Springer
2022-11-01
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| Series: | Discover Oncology |
| Online Access: | https://doi.org/10.1007/s12672-022-00579-x |