Ginsenoside Rg-1 prevents elevated cytosolic Ca2+ via store-operated Ca2+ entry in high-glucose–stimulated vascular endothelial and smooth muscle cells

Ginsenoside Rg-1 prevents elevated cytosolic Ca2+ via store-operated Ca2+ entry in high-glucose–stimulated vascular endothelial and smooth muscle cells

Abstract Background Ginsenoside Rg-1 (Rg-1), a triterpenoid saponin abundantly present in Panax ginseng, is a type of naturally occurring steroid with known anti-diabetic and anti-inflammatory effects. In this study, we sought to confirm the effects and mechanisms of action of Rg-1 on store-operated...

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Bibliographic Details
Main Authors: A Young Han, Su Min Ha, You Kyoung Shin, Geun Hee Seol
Format: Article
Language:English
Published: BMC 2022-06-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Ginsenoside Rg-1
Store-operated Ca2+ entry
High glucose
Vascular endothelial cells
Vascular smooth muscle cells
Online Access:https://doi.org/10.1186/s12906-022-03647-5

Internet

https://doi.org/10.1186/s12906-022-03647-5

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